James McCaffrey, who voiced "Max Payne" in the popular video game franchise and also starred in television shows including “Rescue Me,” has died, according to his agent. He was 65.

McCaffrey's talent agent David Elliot confirmed Monday that the New York native passed away Sunday surrounded by family and friends.

According to Variety and Fox News Digital, McCaffrey's cause of death was cancer. The Hollywood Reporter and Fox report the actor was diagnosed with multiple myeloma, a type of cancer that affects bone marrow.

"I was lying next to him and holding his hand when he took his last breath, for which I will forever be grateful," the actor's wife Rochelle Boström told Fox News Digital. "His passing is devastating to so many."

Kevin Dillon, an actor from the show "Entourage," paid tribute to McCaffrey on Instagram Sunday.

"James McCaffrey we were lucky to have known you," Dillon wrote, along with a photo of the actors together. "my best friend you will be missed."

McCaffrey had a 35-year career in television and film. Throughout his career, he appeared in several popular television shows including "Sex and the City," "Law & Order: Criminal Intent," "As the World Turns," "White Collar," "The Following," "Madam Secretary," "Suits," "Jessica Jones" and "Blue Bloods."

On the FX drama "Rescue Me," he portrayed a New York City firefighter killed on Sept. 11 who appears to Denis Leary's main character, who is also a firefighter, over the series' seven-season run, which ended in 2011.

Video game fans knew him for voicing the title role in the "Max Payne" video game franchise. McCaffrey also voiced FBI agent Alex Casey in the 2010 "Alan Wake" video game and this year's sequel, "Alan Wake 2." He voiced other characters in 2019's "Control" and 2008's "Alone in the Dark."

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In 2020, McCaffrey told Saratoga Living his favorite role was that of Jimmy Keefe in the television series "Rescue Me," which he acted in from 2004 to 2011.

He also shared that, despite voicing Max Payne, he wasn't much of a gamer himself.

"I’m not a big fan of video games," he said. "The first time I did Max Payne, it was, like, six hours a day in a sound booth, and it was about 400 pages of script. But, I’ve never seen it, I’ve never played it, I have no desire to. I lack the proper appreciation for video games."

McCaffrey is survived by his wife and daughter Tiernan McCaffrey.

Contributing: The Associated Press

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